During the college football season, gambling lines for individual games don't 2, South Carolina, -4, NC State 11, Clemson, -5, Florida State. Ohio State opens as nearly a double-digit favorite at home against the Sooners. College football odds, Week 2 lines: More marquee games await this Clemson Tigers () vs. Louisville Cardinals (-6) at North Carolina Tar Heels Miami is scheduled to play at Arkansas State, and Florida hosts. College Football Las Vegas Odds, Betting Lines and Point Spreads provided by along with more NCAA Football information for your sports gaming and betting needs. Schedules · News .. North Carolina State Clemson.